Marco Arment:
Previous-me tried to persuade everyone to switch to my setup, but I now know that it's not worth the effort. I'll never know someone else's requirements, environment, or priorities as well as they do. I don't know shit about Windows or Outlook or architecture.You should use whatever works for you. And I no longer have the patience or hubris to convince you what that should be. All I can offer is one data point: what I use, and how it works for me.
My thoughts exactly. His post could have been a page right out of my own journal.